Vaginal dilators in the prevention of vaginal stenosis in patients submitted to gynecological brachytherapy: systematic literature review
DOI:
https://doi.org/10.25758/set.2297Keywords:
Gynecological brachytherapy, Vaginal stenosis, Vaginal dilator, Gynecological cancerAbstract
Introduction – Vaginal stenosis is a gynecological brachytherapy side effect, resulting from damage by ionizing radiation on the vaginal mucosa. Vaginal stenosis is characterized by a narrowing of the vaginal vault, lubrification and elasticity loss, causing discomfort and unwellness, thus decreasing the quality of life of patients. The most used method to minimize and prevent vaginal stenosis is by using vaginal dilators. Methods – Between March and April 2020, research was carried out on Scopus, PubMed and ScienceDirect following the PRISMA guidelines for systematic reviews, to try to establish a consensus regarding the use of vaginal dilators in the prevention of vaginal stenosis after brachytherapy. Results – Vaginal dilation should start from two weeks after completion of brachytherapy, with the frequency of use preferably three times a week, for ten minutes, for at least one year. Given written information and follow-up is very important for patient’s adherence to the use of dilators. Conclusion – The use of vaginal dilators is the most indicated to prevent vaginal stenosis, and its use is recommended two to three times a week, for ten minutes, with a duration of at least one year. The information provided is very important for patient compliance.
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References
Lancaster L. Preventing vaginal stenosis after brachytherapy for gynaecological cancer: an overview of Australian practices. Eur J Oncol Nurs. 2004;8(1):30-9.
Han K, Milosevic M, Fyles A, Pintilie M, Viswanathan A. Trends in the utilization of brachytherapy in cervical cancer in the United States. Int J Radiat Oncol Biol Phys. 2013;87(1):111-9.
Nout RA, Smit VT, Putter H, Jürgenliemk-Schulz IM, Jobsen JJ, Lutgens LC, et al. Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial. Lancet. 2010;375(9717):816-23.
Martins J, Vaz AF, Grion RC, Esteves SC, Costa-Paiva L, Baccaro LF. Factors associated with changes in vaginal length and diameter during pelvic radiotherapy for cervical cancer. Arch Gynecol Obstet. 2017;296(6):1125‑33.
Matos SR, Cunha ML, Podgaec S, Weltman E, Centrone AF, Mafra AC. Consensus for vaginal stenosis prevention in patients submitted to pelvic radiotherapy. PLoS One. 2019;14(8):e0221054.
Silva RD, Rosa LM, Radünz V, Cesconetto D. Evaluation and classification of vaginal stenosis in brachytherapy: instrument content validation for nurses. Texto Contexto – Enferm. 2018;27(2):e5700016.
Trotter K, Cohlmeyer S, Massa L. Gynecological issues for cancer survivors. J Nurse Pract. 2018;14(4):283-8.
Park HS, Ratner ES, Lucarelli L, Polizzi S, Higgins SA, Damast S. Predictors of vaginal stenosis after intravaginal high-dose-rate brachytherapy for endometrial carcinoma. Brachytherapy. 2015;14(4):464-70.
Kachnic LA, Bruner DW, Qureshi MM, Russo GA. Perceptions and practices regarding women’s vaginal health following radiation therapy: a survey of radiation oncologists practicing in the United States. Pract Radiat Oncol. 2017;7(5):356-63.
Bakker RM, Vermeer WM, Creutzberg CL, Mens JW, Nout RA, Kuile MM. Qualitative accounts of patients’ determinants of vaginal dilator use after pelvic radiotherapy. J Sex Med. 2015;12(3):764-73.
Stahl JM, Qian JM, Tien CJ, Carlson DJ, Chen Z, Ratner ES, et al. Extended duration of dilator use beyond 1 year may reduce vaginal stenosis after intravaginal high-dose-rate brachytherapy. Support Care Cancer. 2019;27(4):1425-33.
Cullen K, Fergus K, DasGupta T, Kong I, Fitch M, Doyle C, et al. Toward clinical care guidelines for supporting rehabilitative
vaginal dilator use with women recovering from cervical cancer. Support Care Cancer. 2013;21(7):1911-7.
Brand AH, Do V, Stenlake A. Can an educational intervention improve compliance with vaginal dilator use in patients treated with radiation for a gynecological malignancy? Int J Gynecol Cancer. 2012;22(5):897-904.
Bakker RM, Kuile MM, Vermeer WM, Nout RA, Mens JW, van Doorn LC, et al. Sexual rehabilitation after pelvic radiotherapy and vaginal dilator use: consensus using the Delphi method. Int J Gynecol Cancer. 2014;24(8):1499‑506.
Summerfield J, Leong A. Management of radiation therapy- induced vaginal adhesions and stenosis: a New Zealand survey of current practice. J Med Radiat Sci. 2020;67(2):128-33.
Foerster R, Schnetzke L, Bruckner T, Arians N, Rief H, Debus J, et al. Prognostic factors for long-term quality of life after adjuvant radiotherapy in women with endometrial cancer. Strahlenther Onkol. 2016;192(12):895-904.
Bahng AY, Dagan A, Bruner DW, Lin LL. Determination of prognostic factors for vaginal mucosal toxicity associated with intravaginal high-dose rate brachytherapy in patients with endometrial cancer. Int J Radiat Oncol Biol Phys. 2012;82(2):667-73.
Cerentini TM, Schlöttgen J, Viana da Rosa P, La Rosa VL, Vitale SG, Giampaolino P, et al. Clinical and psychological outcomes of the use of vaginal dilators after gynaecological brachytherapy: a randomized clinical trial. Adv Ther. 2019;36(8):1936-49.
Friedman LC, Abdallah R, Schluchter M, Panneerselvam A, Kunos CA. Adherence to vaginal dilation following high dose rate brachytherapy for endometrial cancer. IntJ Radiat Oncol Biol Phys. 2011;80(3):751-7.
Hanlon A, Small Jr W, Strauss J, Lin LL, Hanisch L, Huang L, et al. Dilator use after vaginal brachytherapy for endometrial cancer: a randomized feasibility and adherence study. Cancer Nurs. 2018;41(3):200-9.
Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097
Bonner C, Nattress K, Anderson C, Carter J, Milross C, Philp S, et al. Chore or priority? Barriers and facilitators affecting dilator use after pelvic radiotherapy for gynaecological cancer. Support Care Cancer. 2012;20(10):2305‑13.
Punt L. Patient compliance with the use of vaginal dilators following pelvic radiotherapy for a gynaecological cancer. J Radiother Pract. 2011;10(1):13-25.
Cullen K, Fergus K, DasGupta T, Fitch M, Doyle C, Adams L. From “sex toy” to intrusive imposition: a qualitative examination of women’s experiences with vaginal dilator use following treatment for gynecological cancer. J Sex Med. 2012;9(4):1162-73
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