Influence of different parameters on the decrease of extra-activity studies myocardial Gated-SPECT

Authors

  • Andreia Rodrigues Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa. Lisboa, Portugal.
  • S. Santos Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa. Lisboa, Portugal.
  • Elisabete Carolino Área Científica de Matemática, Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa. Lisboa, Portugal.
  • Eva Sousa Área Científica de Medicina Nuclear, Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa. Lisboa, Portugal.
  • Lina Vieira Área Científica de Medicina Nuclear, Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa. Lisboa, Portugal.

DOI:

https://doi.org/10.25758/set.664

Keywords:

Myocardial perfusion imaging, Percentage of repetitions of acquisitions, Extra myocardial activity, Technetium agents

Abstract

Introduction – Myocardial perfusion imaging (MPI) is one of the most indicated complementary diagnostic exams in cardiovascular disease. Extra myocardial activity is a recurrent problem in the acquisition and evaluation of functional images. Parameters like the radiotracer (RT), the stress protocol, the ingestion of different aliments; the positioning, and imaging processing interfere with extra-myocardial activity in MPI. The aim of this study is to identify the protocol of MPI at the national level and assess the percentage of repetitions of acquisitions caused by this problem. Methodology – For this study, the population selected was the Nuclear Medicine Services (NMS) in Continental Portugal. Were analyzed 15 surveys answered by the Technical Coordinators of the various NMS. The association of behavior of the variables has been made using descriptive statistics and the Spearman Correlation Coefficient. Results – The percentage of repetitions decrease with 99mTechnetium (Tc)-Tetrofosmine, delayed imaging, eating (water, milk, juice, bread with butter), and with attenuation correction. Conclusion – The results achieved in this study demonstrate that the majority of solutions in NMS produce a decrease in exam repetitions. 

Downloads

Download data is not yet available.

References

Peace RA, Lloyd JJ. The effect of imaging time, radiopharmaceutical, full fat milk and water on interfering extra-cardiac activity in myocardial perfusion single photon emission computed tomography. Nucl Med Commun. 2005;26(1):17-24.

Hara M, Monzen H, Futai R, Inagaki K, Shimoyama H, Morikawa M, et al. Reduction of infracardiac intestinal activity by a small amount of soda water in technetium-99m tetrofosmin myocardial perfusion scintigraphy with adenosine stress. J Nucl Cardiol. 2008;15(2):241-5.

Hofman M, McKay J, Nandurkar D. Efficacy of milk versus water to reduce interfering infra-cardiac activity in 99mTc-sestamibi myocardial perfusion scintigraphy. Nucl Med Commun. 2006;27(11):837-42.

Goel S, Bommireddipalli S, DePuey EG. Effect of proton pump inhibitors and H2 antagonists on the stomach wall in 99mTc-sestamibi cardiac imaging. J Nucl Med Technol. 2009;37(4):233-9.

Boz A, Gungor F, Karayalçin B, Yildiz A. The effects of solid food in prevention of intestinal activity in Tc-99m tetrofosmin myocardial perfusion scintigraphy. J Nucl Cardiol. 2003;10(2):161-7.

van Dongen AJ, van Rijk PP. Minimizing liver, bowel, and gastric activity in myocardial perfusion SPECT. J Nucl Med. 2000;41(8) 1315-7.

Sadeghi R, Kakhki D, Reza V, Zakavi R, Momennezhad M. Persistent sub-diaphragmatic activity on the myocardial perfusion scan with 99mTc-sestamibi. Iran J Nucl Med. 2008;16(1):52-6.

Hurwitz GA, Clark EM, Slomka PJ, Siddiq SK. Investigation of measures to reduce interfering abdominal activity on rest myocardial images with Tc-99m sestamibi. Clin Nucl Med. 1993;18(9):735-41.

Hesse B, Tägil K, Cuocolo A, Anagnostopoulos C, Bardiés M, Bax J. EANM/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology. Eur J Nucl Med Mol Imaging. 2005;32(7):855-97.

Germano G. Technical aspects of myocardial SPECT imaging. J Nucl Med. 2001;42(10):1499-507.

Berman DS, Kiat HS, Train KF, Germano G, Maddahi J, Friedman JD. Myocardial perfusion imaging with technetium-99m-sestambi: comparative analysis of available imaging protocols. J Nucl Med. 1994;35(4):681-8.

Braat SH, Leclercq B, Itti R, Lahiri A, Sridhara B, Rigo P. Myocardial imaging with technetium-99m-tetrofosmin: comparison of one-day and two-day protocols. J Nucl Med. 1994;35(10):1581-5.

Fleischmann S, Koepfli P, Namdar M, Wyss CA, Jenni R, Kaufmann PA. Gated 99mTc-tetrofosmin SPECT for discriminating infarct from artifact in fixed myocardial perfusion defects. J Nucl Med. 2004;45(5):754-9.

Germano G, Berman DS. Physics and technical aspects of gated myocardial perfusion SPECT. In Germano G, Berman DS, editors. Clinical gated cardiac SPECT. 2nd ed. New York: Wiley/Blackwell; 2006. p. 27-42. ISBN 9781405131551

Vieira L, Faria D, Patrina J, Nunes C, Sousa D, Ribeiro L. et al. Estudo da influência do número de ciclos por projecção no cálculo da fracção de ejecção ventricular esquerda em estudos Gated SPECT. Saúde &Tecnologia. 2008;(2):45-55.

Elhendy A, Bax JJ, Poldermans D. Dobutamine stress myocardial perfusion imaging in coronary artery disease. J Nucl Med. 2002;43(12):1634-46.

Cuocolo A, Soricelli A, Pace L, Nicolai E, Castelli L, Nappi A, et al. Adenosine technetium-99m-methoxy isobutyl isonitrile myocardial tomography in patients with coronary artery disease: comparison with exercise. J Nucl Med. 1994;35(7):1110-5.

Münch G, Neverve J, Matsunari I, Schröter G, Schwaiger M. Myocardial technetium-99m-tetrofosmin and technetium-99m-sestamibi kinetics in normal subjects and patients with coronary artery disease. J Nucl Med. 1997;38(3):428-32.

Flamen P, Bossuyt A, Franken PR. Technetium-99m-tetrofosmin in dipyridamole-stress myocardial SPECT imaging: intraindividual comparison with technetium-99m-sestamibi. J Nucl Med. 1995;36(11):2009-15.

Pitman AG, Kalff V, Van Every B, Risa B, Barnden LR, Kelly MJ. Effect of mechanically simulated diaphragmatic respiratory motion on myocardial SPECT processed with and without attenuation correction. J Nucl Med. 2002;43(9):1259-67.

Published

2013-11-15

Issue

Section

Artigos

How to Cite

Influence of different parameters on the decrease of extra-activity studies myocardial Gated-SPECT. (2013). Saúde & Tecnologia, 10, 24-29. https://doi.org/10.25758/set.664