Conhecimentos, crenças e consumo de antibióticos na Europa: uma revisão de âmbito

Authors

  • Graça Andrade H&TRC – Health and Technology Research Center, Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa. Lisboa, Portugal.
  • Andreia Galvão Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa. Lisboa, Portugal.
  • Margarida Gonçalves Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa. Lisboa, Portugal.
  • Ana Grilo H&TRC - Health & Technology Research Center, ESTeSL – Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa. Lisboa, Portugal.
  • André Coelho H&TRC - Health & Technology Research Center, ESTeSL – Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa. Lisboa, Portugal.

DOI:

https://doi.org/10.25758/set.641

Keywords:

Antibiotic consumption, Health beliefs, Knowledge, Europe

Abstract

Background – Excessive and inadequate antibiotic consumption corresponds to a severe public health problem, essentially due to the spread of bacterial resistance. This article aims to carry out a scoping review on knowledge, beliefs, and consumption of antibiotics in the European population and the relationship between these variables, as well as with the sociodemographic variables (age, sex, education, area of residence), aiming at a synthesis of the original research on the topic. Methods – The review was conducted using PubMed, Web of Science, SciELO, and Lilacs databases, including articles published between 2008 and 2021. Of the 246 registers initially obtained, 26 articles met the inclusion criteria. Results – Most studies used self-administered questionnaires as a data collection method. The level of knowledge about antibiotics proved to be quite heterogeneous. However, only a minority of studies have identified a good degree of expertise. In twelve of the studies analyzed, the sociodemographic variables showed a relevant relationship with knowledge about antibiotics, which was better in respondents with a higher level of education, young and middle-aged adults, trained in the health field, or with family members working in the health system. The belief that antibiotics are used to treat illnesses like colds and flu more quickly, is the most frequently reported. The consumption of antibiotics was higher in female respondents with less education. Only a few studies have found a relation between antibiotic consumption with age or area of residence. Conclusions – Studies indicate that, in general, the knowledge level is insufficient to allow an adequate consumption of antibiotics, emphasizing the importance of carrying out more effective campaigns on the use of these drugs, focusing on knowledge and beliefs associated with their inappropriate use. Only then will it be possible to reduce the spread of bacterial resistance.

Downloads

Download data is not yet available.

References

Pinho SC. O consumo de antibióticos em ambulatório de acordo com dados de vendas totais e dados de vendas com prescrição [dissertation]. Faro: Faculdade de Ciências e Tecnologia, Universidade do Algarve; 2014. Available from: http://hdl.handle.net/10400.1/8302

Costa AL, Silva J, Silva Jr AC. Resistência bacteriana aos antibióticos e saúde pública: uma breve revisão de literatura [Bacterial resistance to antibiotics and public health: a brief literature review]. Estação Científica (UNIFAP). 2017;7(2):45-57. Portuguese

Direção-Geral da Saúde. Programa de prevenção e controlo de infeções e de resistência aos antimicrobianos. Lisboa: DGS; 2017.

European Centre for Disease Prevention and Control. Antimicrobial resistance surveillance in Europe 2016 [homepage]. Solna: ECDC; 2017. Available from: https://www.ecdc.europa.eu/en/publications-data/antimicrobial-resistance-surveillance-europe-2016

Loureiro RJ, Roque F, Rodrigues AT, Herdeiro MT, Ramalheira E. O uso de antibióticos e as resistências bacterianas: breves notas sobre a sua evolução [Use of antibiotics and bacterial resistances: brief notes on its evolution]. Rev Port Saude Publica. 2016;34(1):77-84. Portuguese

Ramalhinho I, Gomes LF, Filipe C, Cavaco A, Cabrita J. Padrão de prescrição de antibióticos no Algarve: características do doente e dispersão da terapêutica [Patterns of prescription of antibiotics in the Algarve: patient characteristics and spread of treatment]. Rev Port Saude Publica. 2015;33(2):207-21. Portuguese

McCullough AR, Parekh S, Rathbone J, Del Mar CB, Hoffmann TC. A systematic review of the public’s knowledge and beliefs about antibiotic resistance. J Antimicrob Chemother. 2016;71(1):27-33.

Davis ME, Liu TL, Taylor YJ, Davidson L, Schmid M, Yates T, et al. Exploring patient awareness and perceptions of the appropriate use of antibiotics: a mixed-methods study. Antibiotics. 2017;6(4):23.

Chaw PS, Höpner J, Mikolajczyk R. The knowledge, attitude and practice of health practitioners towards antibiotic prescribing and resistance in developing countries: a systematic review. J Clin Pharm Ther. 2018;43(5):606-13.

Roque F, Soares S, Breitenfeld L, Gonzalez-Gonzalez C, Figueiras A, Herdeiro MT. Portuguese community pharmacists’ attitudes to and knowledge of antibiotic misuse: questionnaire development and reliability. PLoS One. 2014;9(3):e90470.

Scaioli G, Gualano MR, Gili R, Masucci S, Bert F, Siliquini R. Antibiotic use: a cross-sectional survey assessing the knowledge, attitudes and practices amongst students of a school of medicine in Italy. PLoS One. 2015;10(4):e0122476.

Correia MC. Intervenção farmacêutica na compliance da antibioterapia [dissertation]. Coimbra: Faculdade de Farmácia, Universidade de Coimbra; 2014. Available from: http://hdl.handle.net/10316/79725

Kamulegeya A, William B, Rwenyonyi CM. Knowledge and antibiotics prescription pattern among Ugandan oral health care providers: a cross-sectional survey. J Dent Res Dent Clin Dent Prospects. 2011;5(2):61-6.

Jamshed S, Padzil F, Shamsudin SH, Bux SH, Jamaluddin AA, Bhagavathula AS, et al. Antibiotic stewardship in community pharmacies: a scoping review. Pharmacy. 2018;6(3):92.

Carpenter CJ. A meta-analysis of the effectiveness of health belief model variables in predicting behavior. Health Commun. 2010;25(8):661-9.

Norris P, Chamberlain K, Dew K, Gabe J, Hodgetts D, Madden H. Public beliefs about antibiotics, infection and resistance: a qualitative study. Antibiotics. 2013;2(4):465-76.

Joaquim AB, Kiatecoski T, Zem PS, Reksidler AB. Antibióticos e resistência microbiana. Rev Cienc Saude Unisantacruz. 2014;3:2-3.

Bunten AK, Hawking MK, McNulty CA. Patient information can improve appropriate antibiotic prescribing. Nurs Pract. 2015;82:61-3.

Grigoryan L, Burgerhof JG, Degener JE, Deschepper R, Lundborg CS, Monnet DL, et al. Determinants of self-medication with antibiotics in Europe: the impact of beliefs, country wealth and the healthcare system. J Antimicrob Chemother. 2008;61(5):1172-9.

Azevedo MM, Pinheiro C, Yaphe J, Baltazar F. Portuguese students’ knowledge of antibiotics: a cross-sectional study of secondary school and university students in Braga. BMC Public Health. 2009;9:359.

Ribeiro M, Pinto I, Pedrosa C. Comportamento da população do concelho de Vizela no consumo de antibióticos [Antibiotics consumption behaviour of the Vizela’s region population]. Rev Port Saúde Pública. 2009;27(2):57-70. Portuguese

Faber MS, Heckenbach K, Velasco E, Eckmanns T. Antibiotics for the common cold: expectations of Germany’s general population. Euro Surveill. 2010;15(35):19655.

Monteiro C, Fontes A, Matos R, Rodrigues AI, Pereira P, Costa MC. Utilização de antibióticos numa amostra da população de Lisboa [Survey on the antibiotic ise in a Lisbon population sample]. Rev Lusófona Cienc Tecnol Saúde. 2010;7(1):21-35. Portuguese

Muras M, Krajewski J, Nocun M, Godycki-Cwirko M. A survey of patient behaviours and beliefs regarding antibiotic self-medication for respiratory tract infections in Poland. Arch Med Sci. 2013;9(5):854-7.

Panagakou SG, Spyridis Ν, Papaevangelou V, Theodoridou KM, Goutziana GP, Theodoridou MN, et al. Antibiotic use for upper respiratory tract infections in children: a cross-sectional survey of knowledge, attitudes, and practices (KAP) of parents in Greece. BMC Pediatr. 2011;11:60.

Matos CR. Resistência bacteriana aos antibióticos como um problema de saúde pública: o papel do farmacêutico enquanto promotor de saúde [dissertation]. Lisboa: Universidade Lusófona de Humanidades e Tecnologias; 2012. Available from: http://hdl.handle.net/10437/3072

Dyar OJ, Howard P, Nathwani D, Pulcini C. Knowledge, attitudes, and beliefs of French medical students about antibiotic prescribing and resistance. Med Mal Infect. 2013;43(10):423-30.

Napolitano F, Izz MT, Di Giuseppe G, Angelillo IF. Public knowledge, attitudes, and experience regarding the use of antibiotics in Italy. PLoS One. 2013;8(12):e84177.

Ramalhinho IM. O uso de antibióticos no Algarve: padrão de utilização, conhecimentos, crenças e comportamentos [dissertation]. Lisboa: faculdade de Farmácia, Universidade de Lisboa; 2013. Available from: http://hdl.handle.net/10451/9661

Ivanovska V, Zdravkovska M, Bosevska G, Angelovska B. Antibiotics for upper respiratory infections: public knowledge, beliefs and self-medication in the Republic of Macedonia. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2013;34(2):59-70.

Raposo NM. Avaliação da compliance de antibióticos na população de Castelo Branco. Castelo Branco: experiência profissionalizante na vertente de farmácia comunitária, hospitalar e investigação. Covilhã: Faculdade de Ciências da Saúde, Universidade da Beira Interior; 2014. Available from: http://hdl.handle.net/10400.6/4880

Lopes HL, Pereira JB, Carvalho MR. O que sabem os utentes sobre antibióticos: um estudo de investigação em duas Unidades de Saúde Familiar [What patients know about antibiotics: a cross-sectional study in two Family Health Units]. Rev Port Med Geral Fam. 2015;31(4):248-54. Portuguese

Pavydė E, Veikutis V, Mačiulienė A, Mačiulis V, Petrikonis K, Stankevičius E. Public knowledge, beliefs and behavior on antibiotic use and self-medication in Lithuania. Int J Environ Res Public Health. 2015;12(6):7002-16.

Fejza A, Kryeziu Z, Kadrija K, Musa M. Pharmacy students’ knowledge and attitudes about antibiotics in Kosovo. Pharm Pract. 2016;14(1):715.

Vallin M, Polyzoi M, Marrone G, Rosales-Klintz S, Wisell KT, Lundborg CS. Knowledge and attitudes towards antibiotic use and resistance: a latent class analysis of a Swedish population-based sample. PLoS One. 2016;11(4):e0152160.

MacAdam A, Kaufman E, Williams S. Knowledge and beliefs of young people about medicines in the UK. Int J Pharm Pract. 2017;25(2):168-71.

Kaae S, Malaj A, Hoxha I. Antibiotic knowledge, attitudes and behaviours of Albanian health care professionals and patients: a qualitative interview study. J Pharm Policy Pract. 2017;10:13.

Ancillotti M, Eriksson S, Veldwijk J, Fahlquist JN, Andersson DI, Godskesen T. Public awareness and individual responsibility needed for judicious use of antibiotics: a qualitative study of public beliefs and perceptions. BMC Public Health. 2018;18(1):1153.

Roope LS, Tonkin-Crine S, Butler CC, Crook D, Peto T, Peters M, et al. Reducing demand for antibiotic prescriptions: evidence from an online survey of the general public on the interaction between preferences, beliefs and information, United Kingdom, 2015. Euro Surveill. 2018;23(25):1700424.

Jakupi A, Raka D, Kaae S, Sporrong SK. Culture of antibiotic use in Kosovo: an interview study with patients and health professionals. Pharm Pract. 2019;17(3):1540.

Ilktac M, Tarabishi MT, Ozbirtan P, Gulcan C, Celik G. A public awareness study about antibiotic consumption habits and antibacterial resistance in north-eastern region of Cyprus. J Infect Dev Ctries. 2020,14(5):463-70.

Michaelidou M, Karageorgos SA, Tsioutis C. Antibiotic use and antibiotic resistance: public awareness survey in the Republic of Cyprus. Antibiotics. 2020;9(11):759.

Pouwels KB, Roope LS, Buchanan J, Morrell L, Tonkin-Crine S, Peters M, et al. Awareness of appropriate antibiotic use in primary care for influenza-like illness: evidence of improvement from UK population-based surveys. Antibiotics. 2020;9(10):690.

Gaygısız Ü, Lajunen T, Gaygısız E. Community use of antibiotics in Turkey: the role of knowledge, beliefs, attitudes, and health anxiety. Antibiotics. 2021;10(10):1171.

WHO. Antimicrobial resistance: global health report on surveillance. Bull World Health Organ. 2014;1-256.

World Health Organization. WHO report on surveillance of antibiotic consumption: 2016-2018 early implementation [homepage]. Geneva: WHO; 2018. ISBN 9789241514880. Available from: https://www.who.int/publications/i/item/who-report-on-surveillance-of-antibiotic-consumption

Published

2022-11-30

Issue

Section

Artigos de Revisão

How to Cite

Conhecimentos, crenças e consumo de antibióticos na Europa: uma revisão de âmbito. (2022). Saúde & Tecnologia, 27, 18-29. https://doi.org/10.25758/set.641